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Updated: Jul 10, 2025

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RNA结合蛋白 hnRNPU 调节了多发性骨髓瘤对 selinexor 的抵抗力

Xin Wang1, Juan Xu1, Qun Li2

  • 1Department of Hematology, West China Hospital, Sichuan University, China.

Cancer letters
|November 20, 2023
PubMed
概括

异质核核核糖核蛋白U (hnRNPU) 调节对 selinexor 的敏感性,这是一种多发性骨髓瘤 (MM) 治疗. 较低的hnRNPU表达增强了来自selinexor的MM细胞死亡,这表明它是一种预测性生物标志物.

关键词:
多发性骨髓瘤是一种多发性骨髓瘤.这是一种RNA结合蛋白.这就是Selinexor.一个XPO1一个XPO1一个XPO1这就是为什么 hnRNPU.

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