运动能力与疲劳,呼吸障碍和肺功能之间的关系在非住院的长期COVID患者中
Kiri Lovise Njøten1,2, Birgitte Espehaug1, Liv Heide Magnussen1
1Department of Health and Functioning, Western Norway University of Applied Sciences, Bergen, Norway.
Physiological reports
|November 20, 2023
概括
长期COVID影响功能状态,疲劳和呼吸障碍很常见. 这项研究发现,在非住院患者中,运动能力与呼吸障碍和肺功能有关,但与疲劳无关.
科学领域:
- 肺部医学 肺部医学
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
背景情况:
- 长期COVID是一个全球性的健康挑战,影响患者的功能状态,报告了200多种症状.
- 疲劳,呼吸困难和运动障碍是最常见的长期COVID症状之一.
- 了解这些障碍对于有效的患者管理和康复至关重要.
研究的目的:
- 在非住院的长期COVID患者中描述运动能力,疲劳,呼吸障碍和肺功能.
- 调查运动能力与疲劳和呼吸障碍等关键症状之间的相关性.
- 检查运动能力和肺功能测试之间的关系.
主要方法:
- 65名非住院的长期COVID患者 (54%为女性,平均年龄39岁) 被纳入.
- 参与者进行了螺旋测量,心肺运动测试 (CPET),爬楼梯测试 (SCT) 和30秒坐立测试 (30STST).
- 疲劳和呼吸障碍水平使用验证的问卷进行了评估.
主要成果:
- 95%的参与者报告疲劳,其中65%经历严重疲劳. 66%的人报告呼吸障碍.
- 65%的患者的平均峰值氧气吸收 (V̇O2峰) 处于正常范围内 (预测≥85%).
- 降低V̇O2peak和更长的SCT时间与呼吸障碍增加和一氧化碳 (DLCO) 扩散能力降低相关,但不是疲劳. 30STST的表现与疲劳和呼吸障碍有关.
结论:
- 在非住院的长期COVID患者中,运动能力受损与呼吸障碍和肺部扩散能力降低有关.
- 虽然体力炼测试与呼吸障碍相关,但它们与疲劳的关联不太清楚,这表明复杂的症状相互作用.
- 这些发现凸显了针对性干预的必要性,以解决长期COVID康复中的运动限制和呼吸道症状.
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