优化大型现实世界数据分析与R的板文件:一个一步一步的教程
Abdullah I Abdelaziz1, Kent A Hanson1, Charles E Gaber1
1Department of Pharmacy Systems, Outcomes and Policy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, USA.
Pharmacoepidemiology and drug safety
|November 20, 2023
概括
本研究提出了一种高效的基于R的方法,用于分析大型现实世界证据 (RWE) 数据,减少存储需求并提高分析速度. 这种方法支持RWE研究中的开放科学实践.
科学领域:
- 医疗信息学 医疗信息学
- 数据科学数据科学数据科学
- 药物监督 药物监督 药物监督
背景情况:
- 现实世界证据 (RWE) 研究通常涉及大型数据集,对开源编程语言构成挑战.
- 促进RWE研究中的开放科学实践需要有效的数据处理方法.
研究的目的:
- 为RWE研究人员展示一种有效的方法,即利用R编程语言进行大数据分析.
- 为了实现RWE分析任务,从队列构建到最终报告,使用开源工具.
主要方法:
- 开发了一个R函数来将Merative Marketscan数据 (2017-2019) 转换为R兼容性的方块格式.
- 将转换和原始数据 (SAS) 之间的数据大小,数值一致性和探索任务运行时间进行比较.
- 进行了一项文学研究的简化复制,以展示实际应用.
主要成果:
- 转换的数据大小为原始文件的10%-43%,表明存储效率高.
- 使用SAS的转换数据的R探索任务通常表现优于使用SAS的原始数据运行时间.
- 使用转换的数据,证明了RWE研究的高效实施.
结论:
- 介绍了一种免费和高效的解决方案,使开源编程语言能够使用大型现实数据库.
- 这种方法有助于在现实世界证据研究中采用开放科学实践.
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