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交叉肢体支架移植配置对腹腔大动脉动脉瘤干预疗法的血液动力学影响
Yanqing Xie1, Yating Zhu2, Yike Shi3
1Department of Cardiology, The First Affiliated Hospital of Ningbo University, Ningbo, 315020, China.
Cardiovascular engineering and technology
|November 20, 2023
概括
优化交叉四肢 (CL) 支架-移植配置,特别是主要身体长度和横角,是有效腹腔大动脉瘤 (AAA) 治疗的关键. 调整这些参数可以减少对移植物的力,改善患者的治疗结果.
科学领域:
- 生物医学工程 生物医学工程
- 心血管研究研究心血管研究
- 医疗成像医学成像
背景情况:
- 交叉四肢 (CL) 技术是治疗腹腔大动脉动脉瘤 (AAA) 的标准内血管方法.
- 支架移植配置显著影响术后血动力学,影响治疗的有效性和安全性.
研究的目的:
- 为了研究血液动力学和CL支架-移植配置之间的关系.
- 分析CL支架-移植几何学的变化如何影响血液动力学参数.
主要方法:
- 使用患者特定的CTA数据创建了五种不同的CL支架移植几何模型.
- 进行了数值模拟来分析流动模式,壁应力 (WSS),局部正常化螺旋性 (LNH),压力下降和位移力.
主要成果:
- 主体长度增加与螺旋流和WSS相关,但也导致局部的二次流和WSS振荡.
- 增加主体长度或减少横角减少了对支架移植的移位力.
- 截面角的降低对整体血液动力学特征没有显著影响.
结论:
- 对于成功的AAA内血管修复,CL支架-移植配置至关重要.
- 血液动力学分析为在接受CL手术的AAA患者中指导支架选择和治疗计划提供了宝贵的见解.
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