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现象型的整合提高了功率,并保持了大抑郁症主要抑郁症的生物库基因研究的特异性

Andrew Dahl1, Michael Thompson2, Ulzee An2

  • 1Section of Genetic Medicine, University of Chicago, Chicago, IL, USA. andywdahl@uchicago.edu.

Nature genetics
|November 21, 2023
PubMed
概括

在生物库中整合浅层和深层的表型可以改善主要抑郁症 (MDD) 的遗传研究. 现型归因提高了全基因组关联研究 (GWAS) 的功率和多基因风险评分 (PRS) 预测准确度.

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