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饮食糖尿病风险降低得分 (DDRRS) 和乳腺癌风险:伊朗的一项病例对照研究
Milad Mohammadzadeh1, Alireza Bahrami1, Fatemeh Abdi2
1Department of Clinical Nutrition and Dietetics, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
旨在降低2型糖尿病风险的饮食没有显示与乳腺癌风险的总体关联. 然而,这种饮食方法可能有助于预防绝经后妇女患乳腺癌.
科学领域:
- 营养科学 营养科学
- 在瘤学瘤学.
- 流行病学 流行病学
背景情况:
- 2型糖尿病和胰岛素抵抗与瘤开始有关.
- 针对糖尿病风险的饮食干预措施可能会影响癌症的发展.
研究的目的:
- 调查饮食糖尿病风险降低得分与伊朗妇女乳腺癌风险之间的关联.
- 探索糖尿病风险降低饮食在乳腺癌中的潜在预防作用.
主要方法:
- 一项涉及136例乳腺癌病例和272例对照者的病例控制研究.
- 通过168项食物频率问卷 (FFQ) 评估饮食摄入量.
- 多变量逻辑回归用于分析饮食分数三分之一的乳腺癌几率比率 (OR).
主要成果:
- 在调整了混因子后,在饮食糖尿病风险降低得分和整体乳腺癌风险之间没有发现显著的关联 (OR = 0.65,95% CI:0.37-1.14).
- 在坚持饮食糖尿病风险降低得分 (OR = 0.43,95% CI:0.19-0.99) 的绝经后妇女中观察到乳腺癌风险降低.
结论:
- 该研究发现,饮食糖尿病风险降低得分和乳腺癌风险之间没有总体显著的关系.
- 坚持一种降低2型糖尿病风险的饮食可能在乳腺癌中起到预防作用,特别是在绝经后的妇女中.
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