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通过DNMT3a介导的PPARγ甲基化,通过调节NF-κB通路,促进椎间盘退化

Peng Cheng1,2, Hang-Zhi Wei3, Hai-Wei Chen1

  • 1Department of Emergency Medicine, Lanzhou University Second Hospital, Lanzhou, Gansu, PR China.

Journal of cellular and molecular medicine
|November 21, 2023
PubMed
概括

DNA甲基转移酶3a (DNMT3a) 通过促进细胞死亡和基质分解,驱动椎间盘退化 (IVDD). 抑制DNMT3a为治疗IVDD提供了一个潜在的治疗策略.

关键词:
在 DNMT3a 中使用.在PPARγ中,PPARγ是PPARγ椎间盘退化 椎间盘退化腰部疼痛 腰部疼痛 腰部疼痛

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