主体特异性微生物群对于饮食特异性代谢平衡是必需的
bioRxiv : the preprint server for biology
|November 21, 2023
概括
宿主特定的微生物组对于维持哺乳动物的代谢平衡至关重要. 引入外来微生物群,就像人类微生物群一样,未能提供代谢益处,并导致小鼠的缺陷.
科学领域:
- 微生物组研究的研究.
- 哺乳动物生理学 哺乳动物生理学
- 代谢的恒常化是代谢的恒常化.
背景情况:
- 确定了宿主特异性微生物群落在哺乳动物免疫健康中的作用.
- 然而,宿主新陈代谢生理学恒温的依赖性对专属细菌群落的依赖性仍然不清楚.
结论:
- 一个共同进化的,宿主特异性的微生物组对于代谢灵活性和恒温是必不可少的.
- 外来微生物群落由于殖民抵抗和代谢物功能障碍而提供有限的代谢益处.
- 微生物组的宿主特异性是宿主代谢健康的关键因素.
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