脑内皮层Glutamatergic和GABAergic投影双向控制区分和广义化海马体表现的表现
bioRxiv : the preprint server for biology
|November 21, 2023
概括
侧腔内耳皮层 (LEC) 的谷氨酸和GABAergic投射双向控制记忆. 在LEC中,Glutamatergic输入使模式分离成为可能,而GABAergic输入则驱动对象识别的模式完成.
科学领域:
- 神经科学是一个神经科学.
- 计算神经科学是一种神经科学.
- 系统神经科学 系统神经科学
背景情况:
- 区分和概括对于记忆和对象识别至关重要,依赖于模式分离和完成.
- 控制这些计算的精确神经电路在很大程度上是未知的.
结论:
- 证明LEC GLU和LEC GABA投影可以动态调节模式分离和完成.
- 这些发现阐明了记忆中的上下文歧视和概括的电路机制.
- 这些投影之间的相互作用为神经元表示提供了一个动态范围.
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