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Updated: Jul 10, 2025

X-Ray Crystallography to Study the Oligomeric State Transition of the Thermotoga maritima M42 Aminopeptidase TmPep1050
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X-Ray Crystallography to Study the Oligomeric State Transition of the Thermotoga maritima M42 Aminopeptidase TmPep1050

Published on: May 13, 2020

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细菌二叶酸减少酶的原子分辨率晶体结构中的X射线驱动化学和形状异质性

Nathan Smith1, Alexander R Horswill2, Mark A Wilson1

  • 1Department of Biochemistry and Redox Biology Center, University of Nebraska-Lincoln, Lincoln, NE, 68588.

bioRxiv : the preprint server for biology
|November 21, 2023
PubMed
概括

X射线可以意外地驱动细菌二叶酸减少酶 (DHFR) 酶中的化物转移,类似于它们的自然催化功能. 这一发现揭示了X射线光还原作为研究酶动态和抗生素点的工具.

关键词:
不同类型的B因子.结晶学障碍是一种结晶学障碍.酶动力学 酶动力学化物转移转移化物辐射损伤 辐射损伤

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