交联的TMS/fMRI显示,威胁降低了dlPFC介导的情绪处理的上下调节
medRxiv : the preprint server for health sciences
|November 21, 2023
概括
无法预测的威胁会损害大脑的自上而下的情绪控制,特别是减少右背侧前额皮层 (dlPFC) 对焦虑相关区域的影响. 这表明dlPFC刺激可能有助于治疗焦虑症.
科学领域:
- 神经科学是一个神经科学.
- 认知神经科学 认知神经科学
- 精神病学是一个精神病学.
背景情况:
- 右背侧前额皮层 (dlPFC) 参与认知情绪调节.
- 直接的因果关系证据和威胁对dlPFC的自上而下的监管的影响仍然不清楚.
结论:
- 威胁通过削弱对左侧岛屿等区域的自上而下的控制来减少dlPFC介导的情绪处理.
- 这些发现支持了正确的dlPFC刺激作为焦虑症干预措施的潜力.
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