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Updated: Jul 15, 2026

Analysis of Simian Immunodeficiency Virus-specific CD8+ T-cells in Rhesus Macaques by Peptide-MHC-I Tetramer Staining
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Analysis of Simian Immunodeficiency Virus-specific CD8+ T-cells in Rhesus Macaques by Peptide-MHC-I Tetramer Staining

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针对生殖线的SOSIP三元体免疫引发前体CD4结合部位的向,在婴儿中广泛中和抗体

Ashley N Nelson1, Xiaoying Shen2, Sravani Vekatayogi2

  • 1Department of Pediatrics, Weill Cornell Medicine; New York, NY, USA.

bioRxiv : the preprint server for biology
|November 21, 2023
PubMed
概括

一种使用B细胞系设计的HIV包裹SOSIPs的新型疫苗策略在婴儿中成功诱导青春期前广泛中和抗体 (bnAbs). 这种早期儿童免疫接种方法对预防青少年艾滋病毒感染有很大希望.

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Respiratory Syncytial Virus Disease01:29

Respiratory Syncytial Virus Disease

Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...