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神经细胞的糖原分解通过酸路径缓解陶病症 - - 中介氧化应激减轻氧化应激

Sudipta Bar1, Kenneth A Wilson1, Tyler A U Hilsabeck1

  • 1Buck Institute for Research on Aging, Novato, CA 94947, USA.

Research square
|November 21, 2023
PubMed
概括

激活糖原酸化酶 (GlyP) 会分解神经元中的糖原,改善模型中的病症状. 这一过程减轻了氧化压力,并为阿尔茨海默氏症等神经退行性疾病提供了新的治疗点.

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