[骨/软骨免疫调节水凝:构建策略和应用]
Maoyuan Li1,2, Guoshuang Zheng2, Jiahui Yang2
1Zhongshan Clinical College of Dalian University, Dalian Liaoning, 116001, P. R. China.
概括
骨/软骨免疫调节水凝被设计用于调节免疫反应,促进组织再生. 这些先进的材料显示出治疗骨和软骨缺陷的前景.
科学领域:
- 生物材料科学 生物材料科学
- 免疫学 免疫学 免疫学
- 再生医学是一种再生医学.
背景情况:
- 骨质中缺陷带来了重大的临床挑战.
- 目前的治疗方法在完全恢复骨和软骨功能方面往往缺乏有效性.
- 免疫反应在组织愈合和再生中起着至关重要的作用.
结论:
- 免疫调节水凝通过调节宿主免疫反应来促进骨质状元的修复.
- 它们在骨质突缺陷修复方面表现出广泛的应用前景.
- 进一步的基础和临床研究是必要的临床翻译.
相关概念视频
Bone Structure
Within the skeletal system, the structure of a bone, or osseous tissue, can be exemplified in a long bone, like the femur, where there are two types of osseous tissue: cortical and cancellous.
Bone Remodeling
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
Regulation of Hematopoietic Stem Cells
All blood and immune cells are produced from the multipotent hematopoietic stem cells (HSCs) by the process of hematopoiesis. However, they all have a limited life span. In addition, many are depleted in immune surveillance or combatting an injury or infection. This makes blood one of the most regenerative tissues. Hematopoiesis helps replenish these blood and immune cells, restoring the body's normal functioning. However, overproduction of blood and immune cells can make them cancerous or...


