相关实验视频

Updated: Jul 10, 2025

Modification and Functionalization of the Guanidine Group by Tailor-made Precursors
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Modification and Functionalization of the Guanidine Group by Tailor-made Precursors

Published on: April 27, 2017

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简单合成Fmoc-N-Me-AA-OH使用2-CTC树脂作为临时和可重复使用的保护组的协议

Tanya Román1,2,3, Gerardo Acosta3,4, Constanza Cárdenas1

  • 1Núcleo Biotecnología Curauma, Pontificia Universidad Católica de Valparaíso, Valparaíso 2373223, Chile.

Methods and protocols
|November 21, 2023
PubMed
概括

这项研究提出了一种新的N-甲基化氨基酸 (Fmoc-N-Me-AA-OHs) 固相合成方法,提高了的生物可用性. 开发的方法为类药物开发中必不可少的构建块提供了高产量和纯度.

关键词:
这是2-CTC树脂.这是一种N-甲基化.阿尔法和β氨基酸的氨基酸.

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