相关实验视频
Updated: Jul 10, 2025

10:36
Probiotic Studies in Neonatal Mice Using Gavage
Published on: January 27, 2019
19.5K
肠道微生物群将证据从母亲转移到新生儿身上
Gabriele Luiza Caprara1, Otávio von Ameln Lovison2,3,4, Andreza Francisco Martins2,3,4
1Programa de Pós-Graduação em Saúde da Criança e do Adolescente, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil. gabriele.nutri@yahoo.com.br.
European journal of pediatrics
|November 21, 2023
概括
母亲的肠道微生物群转移到新生儿身上,影响婴儿肠道微生物群的发展. 阴道分娩显示,与剖腹产相比,转移的可能性更高,影响了生命早期的健康结果.
科学领域:
- 微生物学 微生物学
- 人类微生物组 人类微生物组
- 母婴健康 母婴健康
背景情况:
- 生命早期的微生物群组成与未来的健康结果有关.
- 了解母婴微生物群的转移对于婴儿健康至关重要.
- 这项研究调查了巴西队列中的微生物群转移.
研究的目的:
- 调查肠道微生物群从母亲转移到新生儿的情况.
- 检查微生物群转移与传递方式之间的关系.
- 评估ASV特异性转移及其与母体微生物群丰度的相关性.
主要方法:
- 从孕妇和新生儿收集门粘膜样本.
- 使用16S rRNA基因测序 (V3-V4区域) 分析了微生物组的组成.
- 利用费舍尔的精确测试,赔率比率 (OR) 和加权转移比率 (WTR) 来评估转移的可能性和交付方式的影响.
主要成果:
- 与交付方式相关的显著ASVs (p < 0.05) 被确定.
- 阴道分娩显示了微生物群转移的积极概率 (OR = 2.184,WTR = 1.852).
- 观察到母体ASV丰度和传输可能性之间存在负相关性,这两种分娩方式对剖腹产显著 (p = 0.0083).
结论:
- 孕产妇的肠道微生物组与婴儿的肠道微生物组有关,证实了ASV特异性的转移.
- 分娩方式显著影响母婴微生物群的转移.
- 研究结果强调了早期微生物殖民对婴儿健康的重要性.
相关概念视频
Anatomy of the Intestines
72.1K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
72.1K
Bacterial Flora of the Large Intestine
473
The gut microbiome is formed by a vast and diverse community of bacteria that colonizes our large intestine. These bacteria start residing in the gut from birth and continue diversifying throughout life, influenced by factors such as diet, lifestyle, and stress. The gut bacterial community also includes bacteria from food and those that enter the colon through the anus.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
473
What is Monogastric Digestion?
71.2K
The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
71.2K

