亚托邦性皮肤炎的临床多样性
Karishma Daftary1, Raj Chovatiya1
1Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Cutis
|November 21, 2023
概括
亚托邦性皮肤炎 (AD) 在皮肤有色 (SOC) 的患者中呈现不同. 本综述强调了阿尔茨海默病在种族和种族群体的不同临床表现,强调皮肤科医生需要识别这些变异.
科学领域:
- 皮肤病学 皮肤病学
- 免疫学 免疫学 免疫学
- 遗传学 是一个遗传学.
背景情况:
- 亚托皮炎 (AD) 是一种普遍存在的慢性炎症性皮肤疾病.
- 阿尔茨海默病的临床表现在不同人群中可能有很大差异.
- 以前的基于种族的研究指出,皮肤颜色 (SOC) 的AD表型存在差异.
研究的目的:
- 审查和描述亚托皮性皮肤炎的临床多样性.
- 在种族,种族和SOC的背景下了解AD表型差异.
- 通知皮肤科医生关于多种不同皮肤类型的AD异质性.
主要方法:
- 进行了对现有文献的叙事审查.
- 专注于研究检查阿托皮性皮肤炎的临床表型的研究.
- 分析了与种族,民族和皮肤颜色有关的差异.
主要成果:
- 在AD临床表型中观察到显著的种族和种族差异.
- 在理解这些观察到的差异背后的因果因素方面存在承认的局限性.
- 突出了AD病变形态和炎症严重程度的异质性.
结论:
- 皮肤科医生必须意识到亚托邦性皮肤炎的不同临床表现.
- 在所有皮肤类型中识别AD的变化对于有效的管理至关重要.
- 需要进一步的研究来阐明观察到的表型差异的潜在原因.
相关概念视频
Skin Diseases and Disorders
3.9K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
3.9K
Changes in Skin Color: Clinical Perspectives
2.0K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
2.0K
Hypersensitivities
684
Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
684
Skin Cancer
4.2K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.2K
Diversity of Antigen Receptors
595
Antigen receptors are essential components of the immune system crucial in defending the body against foreign invaders. These receptors are present on the surface of B and T cells, enabling them to recognize antigens and mount an appropriate immune response.
Before encountering any antigen, lymphocytes express these receptors. On B cells, the antigen receptor is a membrane-bound antibody molecule called BCR; on T cells, it is a T cell receptor or TCR. B and T cell receptors are composed of two...
Before encountering any antigen, lymphocytes express these receptors. On B cells, the antigen receptor is a membrane-bound antibody molecule called BCR; on T cells, it is a T cell receptor or TCR. B and T cell receptors are composed of two...
595
Cross-reactivity
31.2K
Overview
31.2K


