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瑞士的先天性梅毒:一项回顾性队列研究,2010年至2019年

Gioia Scherler¹, Maren Tomaske², Vincenzo Cannizzaro³

¹Division of Infectious Diseases and Hospital Epidemiology, University Children's Hospital Zurich, Zurich, Switzerland.

Swiss medical weekly

|November 21, 2023

概括

尽管孕产妇梅毒的病例有所增加,但在2010-2019年期间,在苏黎世没有发生任何先天性梅毒病例. 有效的梅毒怀孕查可能防止了先天性梅毒的传播.

科学领域:

公共卫生公共卫生
传染性疾病传染性疾病
儿科儿科儿科

背景情况:

2006年至2009年间,梅毒在瑞士再次出现,有记录的先天性梅毒病例.
瑞士苏黎世州的梅毒发病率最高.

研究的目的:

重新评估2010-2019年间在苏黎世州出生的儿童中对母乳梅毒暴露和先天梅毒的发病率.
评估梅毒怀孕查在预防先天性梅毒的有效性.

主要方法:

通过医院记录和参考实验室数据库,通过母体查评估梅毒的苏黎世 (2010-2019) 出生的儿童被确定.
包括标准包括出生在苏黎世,对梅毒的评估,以及在诊断时的1岁以下的年龄.
数据与联邦公共卫生局 (FOPH) 的流行病学信息进行了比较.

主要成果:

评估了17名儿童对潜在的母性梅毒暴露的情况.
六名儿童真实暴露于无症状的母性梅毒;11名母亲患有过去感染的残留抗体.
在研究期间没有观察到任何先天性梅毒病例.

结论:

尽管梅毒率上升,但在苏黎世 (2010-2019) 没有发现任何先天性梅毒病例.
梅毒怀孕查似乎有效地预防先天性梅毒,通过及时诊断和治疗孕产妇感染.

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