吸烟与背部疼痛之间的关联:一项前性队列研究,涉及438,510名参与者
Hao-Ran Xu1,2,3, Yong-Hui Zhang1,2, Thanh Luan Ngo2
1Department of Rehabilitation Medicine, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Journal of global health
|November 21, 2023
概括
吸烟显著增加了背部疼痛 (BP) 的风险,尤其对女性来说. 戒烟或减少吸烟,包括每天 (CPD) 和每包 (PY) 的香烟,可以有效降低血压的发生率.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 临床研究 临床研究
背景情况:
- 吸烟是已知的背部疼痛 (BP) 的风险因素,但对剂量反应关系和纵向证据的定量数据有限.
- 了解各种吸烟暴露对BP发生率的影响对于全球戒烟努力和初级预防策略至关重要.
研究的目的:
- 调查不同与吸烟有关的暴露 (吸烟状态,每天吸烟,包装年) 与背部疼痛发生率之间的关联.
- 为支持戒烟和预防背痛提供量化证据.
主要方法:
- 一项前性队列研究利用了2006-2010年间招募的438,510名英国生物库参与者的数据,在基线时没有背痛.
- 到2022年4月后续,提取有关吸烟状态 (SS),每天香烟 (CPD) 和包装年 (PY) 的数据.
- 分析采用了考克斯的比例危险模型,对共变量,多重归算和人口归因分数进行了调整.
主要成果:
- 在平均12.98年的随访期间,31,467名参与者出现了背部疼痛.
- 过去的吸烟者 (1.13) 和现在的吸烟者 (1.50) 的发病率更高.
- 吸烟>30 CPD或>30 PY增加了危险比率 (HRs) 到1.45. 与男性相比,女性吸烟者患高血压的风险更高. 不吸烟,戒烟和减少CPD/PY可以分别降低7.8%,5.4%,9.8%和18.0%的血压风险.
结论:
- 长期吸烟,每日吸烟量增加,吸烟强度增加都与背部疼痛风险增加有关.
- 吸烟和背部疼痛之间的关联在女性吸烟者中更为明显.
- 戒烟和减少吸烟量和强度是预防背痛的有效策略.
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