月经周期阶段和排卵对唾液皮质醇唤醒反应的影响
Lisa Haase1, Antonia Vehlen2, Julia Strojny2
1Biological and Clinical Psychology, Department of Psychology, University of Trier, Trier, Germany; Institute for Cognitive and Affective Neuroscience, University of Trier, Trier, Germany.
女性的皮质醇唤醒反应 (CAR) 不会受到月经周期的显著影响,包括排卵阶段. 这项研究没有发现CAR和荷尔蒙变化之间的联系,这表明对周期变化的强度.
科学领域:
- 内分泌学 在内分泌学.
- 心理神经内分泌学心理学
- 时间生物学 时间生物学
背景情况:
- 皮质醇唤醒反应 (CAR) 是白天皮质醇节律标志物.
- 以前的研究表明,月经周期阶段,特别是排卵,会影响CAR.
- 这导致建议避免在排卵阶段采样.
研究的目的:
- 复制关于CAR月经周期调节的发现.
- 为了研究毛囊,排卵和质阶段的CAR变化.
- 检查CAR与雌激素和孕激素水平的相关性.
主要方法:
- 两项涉及健康,自然骑自行车的女性的研究.
- 在醒来后的多个时间点收集的唾液皮质醇.
- 测量了卵巢类固醇水平;通过测试套件确认了排卵.
主要成果:
- 在整个月经周期中没有观察到CAR的显著差异.
- 没有发现CAR与雌醇或孕激素水平之间的显著关联.
- 控制了符合性等混因素,并验证了循环阶段.
结论:
- 在月经周期期间,CAR似乎对荷尔蒙波动有很强的抵抗力.
- 排卵似乎没有显著改变CAR.
- 需要进一步研究卵巢类固醇对HPA轴和皮质醇水平的影响.
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