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Updated: Jul 10, 2025

Predictive Immune Modeling of Solid Tumors
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[关于免疫检查点抑制剂相关不良事件的预测研究进展]

Jing Zhang1, Xueqin Chen1,2, Shenglin Ma2

  • 1Fourth Clinical Medical College, Zhejiang Chinese Medicine University, Hangzhou 310053, China.

Zhongguo fei ai za zhi = Chinese journal of lung cancer
|November 21, 2023
PubMed
概括

免疫检查点抑制剂彻底改变了癌症治疗,但可能导致严重的免疫相关不良事件. 本综述详细介绍了它们的特征和生物标志物,用于早期检测和风险评估.

关键词:
生物标志物 生物标志物临床因素 临床因素免疫检查点抑制剂 免疫检查点抑制剂与免疫相关的不良事件.

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
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