身体活动,力量和健康以及肺功能之间的纵向关联:英国生物银行队列研究
Ls Katrina Li1, Raisa Cassim2, Jennifer L Perret3
1UniSA Allied Health & Human Performance, University of South Australia, Australia; Allergy and Lung Health Unit, Centre of Epidemiology and Biostatistics, University of Melbourne, Australia; School of Allied Health, Human Services and Sport, La Trobe University, Australia.
Respiratory medicine
|November 21, 2023
概括
保持体力活动和握力对于减缓肺功能衰退至关重要. 较低水平的体力活动和握力与随着时间的推移,肺功能下降的速度更快有关.
科学领域:
- 呼吸系统医学 呼吸系统医学
- 公共卫生 公共卫生
- 运动生理学 运动生理学
背景情况:
- 关于身体活动对肺功能的下降对人口水平影响的证据有限.
- 身体活动,握力和心血管健康被假定会影响肺部健康.
- 这项研究解决了对这些关联的强有力的证据的需求.
研究的目的:
- 为了研究身体活动,握力,心血管健康和肺功能下降之间的纵向关联.
- 检查这些因素如何影响1秒内强迫呼气体积 (FEV1) 和强迫生命能力 (FVC) 的下降速度.
主要方法:
- 利用了来自20111名英国生物库参与者的数据,包括基线 (2006-2010) 和后续 (2012-2014) 肺功能指标.
- 使用国际体育活动问卷评估体育活动,并测量握力和心血管健康状况.
- 使用线性回归来分析对肺功能下降的影响 (FEV1,FVC,FEV1/FVC比率),调整基线值和混因子.
主要成果:
- 在平均6.3年的随访期间,平均FEV1下降了30毫升/年,FVC下降了38毫升/年.
- 持续的低体力活动与FEV1和FVCz-score的加速下降显著相关.
- 握力下降也与FEV1加速下降有关,对心血管健康的相关性较弱.
结论:
- 这项大规模的研究表明,较低的体力活动和握力与加速的肺功能下降有关.
- 虽然效应大小看上去很小,但人口层面的影响却很大.
- 研究结果支持将"肺部健康益处"纳入体力活动指南.
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