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手术前的三维形态瘤特征预测了肝细胞癌中的微血管入侵

Yumeng Li¹, Pengpeng Li², Junjie Ma³

¹School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China; Eastern Hepatobiliary Surgery Hospital, No. 700, Moyu North Road, Jiading District, Shanghai, China (Y.L., P.L., Y.W., Q.T., J.Y., W.Z., G.H.).

Academic radiology

|November 21, 2023

概括

手术前的3D成像可以预测肝癌患者的微血管入侵 (MVI). 表面不规则率 (SIR) 是一个关键指标,有助于手术规划和改善患者的结果.

科学领域:

肝胆道手术是肝胆道的手术.
医学成像医学成像
在瘤学瘤学.

背景情况:

微血管入侵 (MVI) 是肝细胞癌 (HCC) 的关键预后因素.
精确的MVI手术前评估对于指导手术治疗决策至关重要.

研究的目的:

评估三维 (3D) 形态指标在手术前预测MVI的有效性.
评估HCC患者表面不规则率 (SIR) 和MVI之间的相关性.

主要方法:

对156名HCC患者的回顾性分析.
薄层CT扫描和3D重建用于定量分析瘤表面倾斜角度.
计算表面不规则率 (SIR) 作为瘤不规则性的度量.
单变量和多变量逻辑回归分析以确定与MVI的关联.

主要成果:

SIR与MVI显著相关 (OR: 10.667,P < 0.001).SIR与MVI显著相关 (OR: 10.667,P < 0.001).SIR与MVI显著相关 (OR: 10.667,P < 0.001).
多变量分析证实SIR是MVI的独立风险因素.
使用SIR的预测模型实现了0.831的ROC曲线下的面积,表明了高的预测准确度.

结论:

手术前的3D形态指标SIR是HCC中MVI的准确预测器.
在HCC管理中,SIR为临床决策提供了宝贵的工具.
这种方法增强了手术前评估,并可能改善手术结果.

关键词:

肝细胞癌是肝细胞癌.微血管侵袭是一种微血管侵袭.形态特征形态特征形态特征预测预测预测这是一个三维的三维空间.

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