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Updated: Jul 10, 2025

Author Spotlight: Magnetic Fluorescent Bead-Based Dual-Reporter Flow Analysis of PDL1-Vaxx Peptide Vaccine-Induced Antibody Blockade of the PD-1/PD-L1 Interaction
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Author Spotlight: Magnetic Fluorescent Bead-Based Dual-Reporter Flow Analysis of PDL1-Vaxx Peptide Vaccine-Induced Antibody Blockade of the PD-1/PD-L1 Interaction

Published on: July 7, 2023

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细胞融合上调调节PD-L1表达,以逃避免疫监测

Youichi Tajima1, Futoshi Shibasaki2, Hisao Masai3

  • 1Genome Dynamics Project, Department of Basic Medical Sciences, Tokyo Metropolitan Institute of Medical Science, Kamikitazawa, Setagaya-ku, Tokyo, 156-8506, Japan. tajima-yi@igakuken.or.jp.

Cancer gene therapy
|November 22, 2023
PubMed
概括

介质细胞干细胞 (MSC) 与膀癌细胞融合,产生不稳定,快速生长的瘤. 这种细胞融合通过诱导PD-L1促进瘤形成,提供新的癌症免疫治疗点.

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