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自闭症基因PTCHD1的神经转录受保护下游增强器序列的调节

Stephen F Pastore1,2, Tahir Muhammad1,2, Cassandra Stan1

  • 1Molecular Neuropsychiatry & Development (MiND) Lab, Molecular Brain Science Research Department, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, M5T 1RS, Canada.

Scientific reports
|November 22, 2023
PubMed
概括

这项研究确定了控制补丁域含有1 (PTCHD1) 基因表达的关键调控元素. 了解这些机制对于解释与神经发育障碍 (如自闭症谱系障碍 (ASD)) 相关的遗传变异至关重要.

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