慢性阻塞性肺病 (PH-COPD) 相关的肺高血压患者的医疗保健资源利用情况:现实世界的数据分析
Tracey Weiss1, Aimee M Near2, Xiaohui Zhao2
1Center for Observational and Real-World Evidence, Merck & Co., Inc, 351 N Sumneytown Pike, PA, North Wales, 19454, USA. Tracey.Weiss@merck.com.
BMC pulmonary medicine
|November 22, 2023
概括
患有慢性阻塞性肺病 (PH-COPD) 二次性肺高血压的患者的医疗费用比单独患有COPD的患者高得多. 管理并发症和预防住院是减少PH-COPD经济负担的关键.
科学领域:
- 肺部医学 肺部医学
- 医疗保健经济学 医疗保健经济学
- 现实世界的证据 现实世界的证据
背景情况:
- 慢性阻塞性肺病 (PH-COPD) 的二次性肺高血压缺乏对医疗保健成本和驱动因素的现实世界特征.
- 了解这些成本对于有效的患者管理和资源分配至关重要.
研究的目的:
- 量化PH-COPD患者的过度医疗资源利用率 (HCRU) 和成本,与没有PH的COPD患者相比.
- 为了确定与PH-COPD患者群体中医疗保健成本增加相关的患者特征.
主要方法:
- 对IQVIA PharMetrics® Plus数据库 (OCT2014-MAY2020) 的分析.
- 基于索赔的算法来识别PH-COPD患者,与1:1匹配的COPD患者没有PH使用倾向分数.
- 年化HCRU和成本的比较,与PH-COPD患者成本驱动因素的回归分析.
主要成果:
- 2,224名PH-COPD患者与2,224名没有PH的COPD患者进行了匹配.
- 患有PH-COPD的患者每年医疗费用显著增加 (51,435美元与18,412美元相比,p<0.001).
- 住院治疗 (57%) 是主要的成本驱动因素;较高的并发症负担和之前的COPD恶化与成本增加有关.
结论:
- PH-COPD与大量的过度医疗费用有关,主要是由住院治疗引起的.
- 预防住院和管理并发性疾病的战略对于减少PH-COPD的经济负担至关重要.
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