非侵入性神经调节:一种新兴的干预措施,用于胃肠道疾病中的内脏疼痛
Md Jahangir Alam1, Jiande D Z Chen2
1Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, 48109, USA. mdalam@med.umich.edu.
Bioelectronic medicine
|November 22, 2023
概括
非侵入性神经调节提供了一个有希望的新方法来管理胃肠道 (GI) 疾病中的内脏疼痛. 这种疗法调节神经活动,为诸如刺激性肠综合征和功能性消化不良等疾病提供了替代方案.
科学领域:
- 胃肠病学和神经病学
- 疼痛管理 疼痛管理
- 生物医学工程 生物医学工程
背景情况:
- 胃肠道 (GI) 疾病很普遍,内脏疼痛显著影响患者的生活质量,并造成社会成本.
- 由于复杂的病理生理学和疾病异质性,目前对胃肠道疼痛的治疗选择有限.
- 神经调节正在作为一种补充疗法来调节神经活动以缓解疼痛.
研究的目的:
- 审查新兴的非侵入性神经调节技术,用于管理各种胃肠道疾病中的内脏疼痛.
- 评估这些新型治疗方法的有效性,安全性和可行性.
- 阐明作用机制,并确定未来的研究方向,用于治疗胃肠道疼痛的非侵入性神经调节.
主要方法:
- 关于非侵入性神经调节方法的当前文献的综述.
- 分析电气,电磁,化学和光遗传技术.
- 在功能性消化不良,胃衰竭,刺激性肠综合征,炎症性肠病和非心脏性胸痛中评估应用.
主要成果:
- 非侵入性神经调节显示出在一系列胃肠道疾病中减轻内脏疼痛的潜力.
- 新兴技术在调节涉及肠-大脑通信的神经通路方面显示出前景.
- 目前正在收集这些新型干预措施的有效性,安全性和可行性数据.
结论:
- 非侵入性神经调节是一种可行的替代治疗策略,用于控制肠道疾病中的内脏疼痛.
- 需要进一步的研究来优化技术并确认长期的结果.
- 这个领域为改善患者管理和生活质量提供了希望.
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