新兴年轻女性的胃肠道功能和月经周期阶段:一个横截面研究
Sivanne Mendelson1, Preethashree Anbukkarasu2, Jeffrey E Cassisi3
1Department of Psychology, University of Central Florida, Orlando, FL, 32816, USA.
BMC gastroenterology
|November 22, 2023
概括
健康女性的胃肠道 (GI) 症状与月经周期无关. 然而,健康焦虑显著影响胃肠道症状严重程度和腹痛,特别是在月经期间.
科学领域:
- 胃肠病学和妇科病学
- 精神病体医学是一种精神病体医学.
- 肠-大脑轴研究研究
背景情况:
- 女性报告的胃肠道 (GI) 症状比男性更严重,可能受到月经周期的影响.
- 健康焦虑是众所周知的加剧各种疾病症状的因素.
- 肠-大脑相互作用障碍 (DGBI) 评估通常涉及评估肠道功能和心理因素.
研究的目的:
- 为了研究女性在月经周期各阶段的消化道功能差异.
- 评估健康焦虑对胃肠道症状和疼痛的影响.
- 评估标准化临床措施在识别DGBI相关症状变异方面的有用性.
主要方法:
- 一项对603名参与者的调查包括功能性GI评估尺度 (PROMIS-GI®),腹部疼痛尺度/图表和健康焦虑测量.
- 参与者被分为月经周期阶段:月经期,毛囊期,早月经期和月经前期.
- 共同变量的多变量分析 (ANCOVA) 检查了相之间的差异,健康焦虑作为共同变量.
主要成果:
- 在月经周期各阶段之间没有观察到PROMIS-GI得分的显著差异.
- 增加的健康焦虑与更高的胃肠道症状和疼痛水平相关.
- 在月经期间,腹下疼痛明显高于在月经前和月经前的早期和月经前阶段.
- 与对照组相比,患有DGBI诊断的参与者表现出更高的胃肠道症状严重程度和更多的疼痛在多个腹部区域.
结论:
- 健康女性的PROMIS-GI得分不受月经周期阶段的显著影响.
- PROMIS-GI尺度有效地确定了DGBI诊断的女性的症状差异.
- 腹部疼痛映射对于DGBI分类和诊断至关重要.
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