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Updated: Jun 27, 2026

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开发一种机械翻译PK/PD模型,用于三功能NK细胞参与者,以预测急性髓性白血病的首剂量

Siak-Leng Choi1, Delphine Valente1, Angela Virone-Oddos2

  • 1Sanofi, DMPK, Paris, France.

Clinical and translational science
|November 22, 2023
PubMed
概括

研究人员开发了一种用于自然杀手细胞参与者 (NKCE) 的新型转化模型,以估计首次人体剂量. 该模型整合了体外和体内数据,以预测CD123-NKCEs的临床结果,推进先天免疫疗法.

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