在患有结核性硬化综合体的儿童眼科表现
Hanna Maria Öhnell1, Ulrika Kjellström1, Erik Eklund2
1Ophthalmology, Department of Clinical Sciences Lund, Skåne University Hospital, Lund University, Lund, Sweden.
Acta ophthalmologica
|November 22, 2023
概括
结核性硬化综合体 (TSC) 的儿童的眼科发现显示出常见的折射误差和. 大脑视力障碍需要眼科医生更大的意识和调查.
科学领域:
- 眼科医生 眼科 眼科
- 遗传学 是一个遗传学.
- 儿科 儿科 儿科
背景情况:
- 结核性硬化综合体 (TSC) 是一种具有多系统表现的遗传性疾病.
- 在患有TSC的儿童中,经常观察到眼科并发症.
研究的目的:
- 记录瑞典南部儿童TSC患者的眼科发现.
- 为了确定这个队列中折射误差,眼和脑视力障碍的患病率.
主要方法:
- 在1983年至2020年期间被诊断患有TSC的儿科患者的回顾性队列研究.
- 对眼科发现,视力敏,折射误差,,电网膜学和脑视力障碍的医疗记录的审查.
主要成果:
- 在被研究的TSC儿童中,折射误差 (62%) 和视 (16%) 是普遍存在的.
- 视网膜星状细胞瘤 (34%) 和非色斑 (34%) 也很常见.
- 在10名患者的维加巴特林治疗导致30%的患者减少了电网膜学反应.
结论:
- 折射误差和视在儿科TSC中很常见.
- 大脑视力障碍仍然被低诊断,这表明需要提高眼科医生意识.
- 需要进一步研究TSC患者的大脑视力障碍.
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