人的正面极皮质的连接性,以及它参与利用与探索的理论
Edmund T Rolls1,2,3, Gustavo Deco4,5,6, Chu-Chung Huang7,8
1Oxford Centre for Computational Neuroscience, Oxford, United Kingdom.
Cerebral cortex (New York, N.Y. : 1991)
|November 22, 2023
概括
前极皮质帮助人类决定是否利用资源或探索新的选择. 它与奖励系统的连接是这个利用与探索决策过程的关键.
科学领域:
- 神经科学是一个神经科学.
- 认知神经科学 认知神经科学
- 神经成像是一种神经成像.
背景情况:
- 前极对于决策至关重要,特别是利用当前资源和探索替代方案之间的平衡.
- 了解这种利用与探索功能的神经基础,需要对前极连接进行详细的分析.
研究的目的:
- 研究人类前极区域与其他前额和皮层区域的有效和功能连接.
- 提出一个模型,说明前极连接如何支持稳定的目标利用和灵活的探索.
主要方法:
- 利用扩散张力成像 (DTI) 曲谱,静止状态功能连接 (rsFC) 和基于任务的有效连接分析.
- 检查了来自人类结合体项目 (HCP) 的171名参与者的正面极区域和背侧/背前额皮质,轨道前额皮质,前带皮质和其他皮质区域之间的连接性.
主要成果:
- 确定了额头极区域与背侧/背前额叶皮层 (参与工作记忆) 和奖励/非奖励系统 (轨道前额和前带皮层) 之间的显著有效连接.
- 揭示了与叶,下额头和后带带膜区域的连接性.
- 证明了前极连接与奖励系统可能是利用与探索二分法的核心.
结论:
- 额头极皮质可能是自联吸引网络的所在地,这对于在目标剥削期间保持认知稳定至关重要.
- 对前极的奖励相关输入可以破坏这些网络的稳定,促进探索替代目标和策略.
- 提议将前极连接与奖励电路作为利用与探索行为背后的关键机制.
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