评估阻塞性睡眠呼吸暂停与甲状腺眼睛疾病及其活动的风险
Namita Kumari1, Nitish Arora1, Sima Das1
1Oculoplasty and Ocular Oncology Services, Dr. Shroff's Charity Eye Hospital, New Delhi, India.
Indian journal of ophthalmology
|November 22, 2023
概括
阻塞性睡眠呼吸暂停 (OSA) 与甲状腺眼病 (TED) 活动有显著的联系. 虽然OSA会影响TED的活动,但它似乎不会影响整体病情的严重程度.
科学领域:
- 眼科医生 眼科 眼科
- 内分泌学 在内分泌学.
- 睡眠医学 睡眠医学
背景情况:
- 甲状腺眼睛疾病 (TED) 是一种影响轨道的自身免疫性疾病.
- 阻塞性睡眠呼吸暂停 (obstructive sleep apnea,OSA) 是一种常见的睡眠障碍,其特征是重复的上呼吸道崩.
研究的目的:
- 调查阻塞性睡眠呼吸暂停 (OSA) 和甲状腺眼病 (TED) 之间的关联.
- 为了确定OSA对甲状腺眼病活动的影响.
主要方法:
- 一项前性病例控制研究,涉及100名TED患者和138名对照.
- 在两组中使用STOP-Bang调查对OSA进行查.
- 使用临床活动评分 (CAS) 和通过EUGOGO分类进行严重程度分级来评估TED活动.
主要成果:
- 与对照组 (34.78%) 相比,TED患者 (62%) 患有高OSA风险的患病率显著更高.
- 单变量和多变量分析证实了OSA和TED活动之间的显著关联 (OR:4.14,95%CI:1.11-18.85).
- 在OSA和TED的严重程度之间没有发现显著的关联.
结论:
- 阻塞性睡眠呼吸暂停与甲状腺眼病的存在和活动有显著的关联.
- OSA似乎与甲状腺眼病的严重程度无关.
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