能源调整的饮食炎症指数和中国老年人的认知功能:基于人口的横截面研究
Lili Chen1,2, Jinxiu Liu3, Xiuli Li3
1Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, People's Republic of China.
Nutritional neuroscience
|November 22, 2023
概括
通过能量调整的饮食炎症指数 (E-DII) 测量的促炎症饮食与老年人认知障碍和阿尔茨海默病 (AD) 的风险更高有关. 管理饮食性炎症可能有助于预防认知能力下降.
科学领域:
- 老年学是一门学科.
- 营养科学 营养科学
- 神经科学是一个神经科学.
背景情况:
- 受到饮食影响的全身炎症在认知障碍和痴呆症中起作用.
- 了解饮食炎症潜力和认知功能之间的联系对于公共健康至关重要.
研究的目的:
- 调查饮食炎症指数 (E-DII) 与老年人认知功能之间的关联.
- 探索饮食炎症潜力与认知障碍和阿尔茨海默病 (AD) 风险之间的关系.
主要方法:
- 研究了一组2307名60岁以上的成年人.
- 饮食炎症指数 (E-DII) 计算以评估饮食炎症潜力.
- 认知功能使用迷你精神状态检查 (MMSE) 和蒙特利尔认知评估 (MoCA) 进行评估.
- 使用了后勤回归和受限立方线 (RCS) 分析.
主要成果:
- 较高的E-DII得分与认知障碍的风险增加显著相关 (OR=1.56,95%CI=1.25-1.93).
- 与得分最低的人相比,E-DII得分最高的人患阿尔茨海默病的风险更高 (OR=1.98,95%CI=1.49-2.64).
- 在E-DII和认知障碍之间观察到非线性剂量反应关系 (P=0.001).
结论:
- 通过更高的E-DII分数表明的饮食炎症升高与患有认知障碍和AD的风险增加有关.
- 控制饮食性炎症可能是预防认知衰退的关键策略.
- 建议在认知健康方面采用包括饮食管理在内的多学科方法.
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