Jove
Visualize
联系我们

相关概念视频

Antimicrobial Proteins01:23

Antimicrobial Proteins

1.0K
Antimicrobial proteins are important components of the immune system. They aid the body in combating pathogens by either killing them directly or hindering their replication processes. Four main types of antimicrobial substances are interferons, the complement system, iron-binding proteins, and antimicrobial proteins.
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
1.0K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Pathogen-specific host responses define distinct pneumonia endotypes in the human lung.

bioRxiv : the preprint server for biology·2026
Same author

In silico perturbations provide multivariate interpretability in predicting post-lung transplant outcomes.

Scientific reports·2026
Same author

Multi-modal image analysis for large-scale cancer tissue studies within IMMUcan.

Cell reports methods·2025
Same author

DelSIEVE: cell phylogeny modeling of single nucleotide variants and deletions from single-cell DNA sequencing data.

Genome biology·2025
Same author

AI-Driven Antimicrobial Peptide Discovery: Mining and Generation.

Accounts of chemical research·2025
Same author

Author Correction: Integrative spatial and genomic analysis of tumor heterogeneity with Tumoroscope.

Nature communications·2025
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关实验视频

Updated: Jul 10, 2025

Antimicrobial Peptides Produced by Selective Pressure Incorporation of Non-canonical Amino Acids
11:56

Antimicrobial Peptides Produced by Selective Pressure Incorporation of Non-canonical Amino Acids

Published on: May 4, 2018

12.5K

人工智能驱动的抗微生物发现.

Paulina Szymczak1, Ewa Szczurek1

  • 1Faculty of Mathematics, Informatics and Mechanics, University of Warsaw, Banacha 2, 02-097, Warsaw, Poland.

Current opinion in structural biology
|November 22, 2023
PubMed
概括

人工智能 (AI) 通过预测特性和产生新型候选物来加速抗微生物 (AMP) 的发现. 人工智能在打击抗菌素耐药性方面提供了传统抗生素的强大替代品.

科学领域:

  • 计算生物学和生物信息学
  • 药物的发现和开发.
  • 传染病和微生物学

背景情况:

  • 抗菌素耐药性 (AMR) 需要超越传统抗生素的新型治疗策略.
  • 抗微生物 (AMP) 由于其广泛的活性,显示出作为替代品的巨大潜力.
  • 传统的AMP发现方法通常是缓慢和资源密集的.

研究的目的:

  • 审查人工智能 (AI) 驱动的抗微生物 (AMP) 发现的最新进展.
  • 突出应用到AMP研究中的关键AI方法,包括歧视性和生成性方法.
  • 讨论人工智能辅助AMP发现的新兴趋势和未来方向.

主要方法:

  • 利用AI区分器来预测关键性质,如活性和毒性.
  • 采用人工智能生成器用于新型AMP候选人的新设计和模拟生成.
  • 实施受控生成技术,如区分器引导过和条件生成,以优化AMP属性.

主要成果:

  • 人工智能显著提高了AMP发现的效率和范围.
  • 区分模型有效地根据预测的属性识别出有前途的AMP候选人.
  • 生成模型成功地创建了新的AMP序列,并针对所需特征优化了现有的序列.

更多相关视频

Production and Visualization of Bacterial Spheroplasts and Protoplasts to Characterize Antimicrobial Peptide Localization
10:13

Production and Visualization of Bacterial Spheroplasts and Protoplasts to Characterize Antimicrobial Peptide Localization

Published on: August 11, 2018

11.9K
Application of the Intelligent High-Throughput Antimicrobial Sensitivity Testing/Phage Screening System and Lar Index of Antimicrobial Resistance
09:59

Application of the Intelligent High-Throughput Antimicrobial Sensitivity Testing/Phage Screening System and Lar Index of Antimicrobial Resistance

Published on: July 21, 2023

1.3K

相关实验视频

Last Updated: Jul 10, 2025

Antimicrobial Peptides Produced by Selective Pressure Incorporation of Non-canonical Amino Acids
11:56

Antimicrobial Peptides Produced by Selective Pressure Incorporation of Non-canonical Amino Acids

Published on: May 4, 2018

12.5K
Production and Visualization of Bacterial Spheroplasts and Protoplasts to Characterize Antimicrobial Peptide Localization
10:13

Production and Visualization of Bacterial Spheroplasts and Protoplasts to Characterize Antimicrobial Peptide Localization

Published on: August 11, 2018

11.9K
Application of the Intelligent High-Throughput Antimicrobial Sensitivity Testing/Phage Screening System and Lar Index of Antimicrobial Resistance
09:59

Application of the Intelligent High-Throughput Antimicrobial Sensitivity Testing/Phage Screening System and Lar Index of Antimicrobial Resistance

Published on: July 21, 2023

1.3K

结论:

  • 人工智能正在彻底改变抗菌素的发现,为抗菌素耐药性提供了一套强大的工具.
  • 人工智能方法的整合有望加速下一代抗菌剂的开发.
  • 对人工智能驱动的方法的持续研究对于解决AMR的全球挑战至关重要.