指动脉近壁血动力学参数因手传递的振动而改变
Christophe Noël1, Nicla Settembre2
1Electromagnetism, Vibration, Optics laboratory, Institut national de recherche et de sécurité (INRS), Vandœuvre-lès-Nancy, France.
Computers in biology and medicine
|November 22, 2023
概括
手传递的振动显著改变了手指动脉的血动力学,减少了壁剪应力 (WSS) 并影响了神经活动. 这项研究为预防振动诱导的血管风险提供了一个新的框架.
科学领域:
- 生物医学工程 生物医学工程
- 职业健康 职业健康 职业健康
- 心血管生理学心血管生理学
背景情况:
- 持续暴露于手传递的振动会导致血管神经障碍.
- 这些疾病可能源于由于重复的振动暴露而导致手指动脉的血液动力学变化.
- 了解这些生理机制对于预防职业血管疾病至关重要.
研究的目的:
- 在数字动脉中识别关键的血液动力学描述符.
- 为了将这些描述符与特定的振动特征相关联.
- 阐明震动诱导的血管效应背后的生理机制.
主要方法:
- 使用超高频超声波扫描仪和振动振动器对数字动脉进行成像.
- 采用定制的数值程序来建模脉动性流体力学和计算血液动力学描述器.
- 分析了24名健康志愿者的数据,使用统计方法和波形变换.
主要成果:
- 动脉直径,壁剪应力 (WSS) 和WSS时间梯度 (WSSTG) 被确定为关键描述因素.
- 振动暴露使WSS减少了大约三分之一,与振动加速水平成比例.
- 在停止振动时观察到WSSTG的增加和与神经性活动相关的WSS功率的下降.
结论:
- 该研究确定了数字动脉中由于振动暴露的关键血液动力学变化.
- 研究结果表明,改变的WSS和WSSTG可能会对健康产生不良影响.
- 这项研究为制定减轻振动诱导血管风险的策略提供了基础.
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