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Updated: Jul 10, 2025

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作为一种针对 adrenocortical carcinoma 的新向治疗方法,PLK1 抑制剂

Emily Warmington1, Gabrielle Smith1, Vasileios Chortis1

  • 1Institute of Metabolism and System Research, University of Birmingham, Birmingham, UK.

Endocrine connections
|November 22, 2023
PubMed
概括

波罗类激酶1抑制剂 (PLK1i) 对治疗上腺皮质癌 (ACC) 有望,特别是在TP53突变的病例中. 在TP53突变的ACC中PLK1的表达较高与较差的结果相关,这表明PLK1i是向治疗的选择.

关键词:
上皮层癌 (adrenocortical carcinoma) 是一种上皮层癌.分子向疗法分子向疗法波罗样类激酶1 (Polo-like kinase1) 是一种类型的激酶.

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