电心电图左心房异常和心力衰竭的风险
Sunnie Li1, Muhammad Imtiaz Ahmad2, Yabing Li1
1Epidemiological Cardiology Research Center, Section on Cardiovascular Medicine, Department of Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, United States of America.
Journal of electrocardiology
|November 22, 2023
概括
电心电图左心房异常 (ECG-LAA),以V1 (DTNPV1) 中P波的深端阴性表示,与心力衰竭 (HF) 风险增加有关. 这种关联显示了种族差异,表明个性化HF风险评估.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 公共卫生 公共卫生
背景情况:
- 左心房异常 (ECG-LAA) 和心力衰竭 (HF) 的心电图标记之间的关系尚未完全理解.
- 关于ECG-LAA与高频率相关性的种族差异需要进一步研究.
研究的目的:
- 检查ECG-LAA,特别是V1 (DTNPV1) 中P波的深端阴性和心力衰竭 (HF) 之间的关联.
- 调查DTNPV1和HF之间的关系中的潜在种族差异.
主要方法:
- 来自美国第三次全国健康和营养检查调查的8460名参与者的横截面分析.
- ECG-LAA定义为DTNPV1≥100μV,自动测量来自ECG.
- 用于评估DTNPV1与HF史的关联的多变量逻辑回归,对混因素进行调整.
主要成果:
- 在3.2%的参与者中检测到异常的DTNPV1,他们患高血压的患病率明显高 (14.7%与4.8%相比).
- 电脑电图-LAA (异常的DTNPV1) 与98%的高频率增加有关 (OR:1.98;95% CI:1.30-3.01).
- 与白人参与者相比,非白人参与者中DTNPV1和HF之间的关联显著更强 (相互作用p=0.01).
结论:
- 通过异常DTNPV1识别的ECG-LAA是与增加HF风险相关的显著标志物.
- 这项研究强调了心房疾病在HF发展中的作用.
- 观察到的种族差异表明,ECG-LAA可能对个性化高频风险分层有价值.
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