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Updated: Jul 10, 2025

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GRP78-CAR T细胞对抗固体和脑瘤的作用受 GRP78 对T细胞表达的作用控制

Jorge Ibanez1, Nikhil Hebbar1, Unmesha Thanekar1

  • 1Department of Bone Marrow Transplantation and Cellular Therapy, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.

Cell reports. Medicine
|November 22, 2023
PubMed
概括

化学抗原受体 (CAR) T细胞疗法在向癌症方面表现有前途. 研究人员确定了细胞表面葡萄糖调节蛋白78 (GRP78) 作为CAR T细胞针对各种瘤的可行的点.

关键词:
在CAR T细胞中,压力ERER压力ERER压力在 GRP78 中使用.大脑瘤 大脑瘤免疫突触的突触发生.免疫疗法 免疫疗法固体瘤是一种固体瘤.

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