跨性别个人的心律失常
Ana C Berni1, Rachel Wamboldt2, Adrián Baranchuk2
1Departamento de Cardiología, Laboratorio de Arritmias, Hospital Ángeles Pedregal, Ciudad de México, México.
Archivos de cardiologia de Mexico
|November 22, 2023
概括
由于荷尔蒙疗法影响脂质代谢和心脏功能,变性人面临更高的心血管风险. 仔细监测对于管理这些风险和预防不良事件至关重要.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 跨性别者健康 跨性别者健康
背景情况:
- 跨性别者比普通人群有更高的心血管风险.
- 性别确认手术和激素治疗可以破坏脂质代谢,改变身体脂肪的分布,增加胰岛素抵抗.
- 激素疗法与静脉血栓栓塞,中风和心肌梗塞的风险增加有关.
研究的目的:
- 突出跨性别人口中心血管风险升高的原因.
- 检查激素治疗对心血管健康的影响,包括脂质代谢和心脏的电生理特性.
- 强调需要在接受激素治疗的跨性别个体进行主动心血管监测.
主要方法:
- 对跨性别人口心血管风险现有文献的审查.
- 对外源性激素治疗对脂质代谢,身体脂肪,胰岛素耐药性和心脏电生理学影响的分析.
- 检查性激素对心脏功能的影响以及心律失常的可能性.
主要成果:
- 激素疗法可能会对脂质代谢,身体脂肪度和胰岛素抵抗产生负面影响.
- 变性人激素治疗与心血管不良事件的风险增加有关,如静脉血栓栓塞,中风和心肌梗塞.
- 外源性激素的使用可以改变QT间隔,并增加心律失常的风险,包括心房动.
结论:
- 变性人需要专门的心血管风险评估和管理.
- 在开始激素治疗之前,必须仔细考虑心血管风险因素.
- 对接受激素治疗的跨性别者来说,持续监测心血管并发症至关重要.
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