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Updated: Jul 10, 2025

Phosphopeptide Enrichment Coupled with Label-free Quantitative Mass Spectrometry to Investigate the Phosphoproteome in Prostate Cancer
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Sara R Savage1, Yaoyun Zhang2, Eric J Jaehnig1

  • 1Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, Texas, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA.

Molecular & cellular proteomics : MCP
|November 22, 2023
PubMed
概括

这项研究介绍了IDPpub,这是一种深度学习工具,可以挖掘生物医学摘要,以识别和编目数千个酸化地点. 本资源通过为这些地点提供关键的功能和上下文证据,增强对蛋白质组的理解.

关键词:
深度学习是一种深度学习.自然语言处理自然语言处理.素蛋白质组学 素蛋白质组学 素蛋白质组学文本采矿 文本采矿是什么

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Protein Kinases and Phosphatases02:54

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Proteins undergo chemical modifications that trigger changes in the charge, structure, and conformation of the proteins. Phosphorylation, acetylation, glycosylation, nitrosylation, ubiquitination, lipidation, methylation, and proteolysis are various protein modifications that regulate protein activity. Such modifications are usually enzyme-driven.
Protein kinases
Many proteins in the cell are regulated by phosphorylation, the addition of a phosphate group. A family of enzymes called kinases...
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