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Updated: Jul 10, 2025

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
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工程重定向NF-κB/OIP5表达程序,以增强膀癌中瘤对化疗的反应

Binbin Zheng1, Liman Niu1, Haibo Xu1

  • 1Department of Urology, Shenzhen Institute of Translational Medicine, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, International Cancer Center of Shenzhen University, Shenzhen 518039, China; Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.

Science bulletin
|November 22, 2023
PubMed
概括

工程CRISPR系统重新编程膀癌细胞通过准Opa相互作用蛋白5 (OIP5) 来克服药物耐药性. 这种合成生物学方法与纳米颗粒相结合,增强了化疗对瘤的有效性.

关键词:
药物耐药性 药物耐药性 药物耐药性基因电路的基因循环.这就是NF-κBB.在OIP5中,OIP5是OIP5.在RNA工程方面,RNA工程是非常重要的.维克里斯蒂娜 (Vincristine) 是一个名为维克里斯蒂娜的女性.

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