预测在手术切口期间血压变化,使用在sevoflurane麻醉下血管硬度值的最小唤起电流
Daiki Shorin1, Satoshi Kamiya1, Ryuji Nakamura2
1Department of Anesthesiology and Critical Care, Hiroshima University Hospital, 1-2-3 Kasumi, Minami, Hiroshima, 734-8551, Japan.
Scientific reports
|November 22, 2023
概括
血管硬的最小唤起电流 (MECK) 可以预测在sevoflurane麻醉下对疼痛的同情反应,类似于propofol. 这一发现支持MECK作为麻醉管理的多功能索引.
科学领域:
- 麻醉学 麻醉学
- 心血管生理学心血管生理学
- 疼痛管理 疼痛管理
背景情况:
- 阿片类药物敏感性各不相同,需要精确的麻醉管理.
- 在propofol麻醉下对 nociception 的同情反应可以通过MECK进行预测.
- 在挥发性麻醉条件下MECK的实用性仍然未被探索.
研究的目的:
- 为了调查MECK是否可以预测在sevoflurane麻醉期间对 nociceptive刺激的同情反应.
- 为了评估MECK和在sevoflurane下皮肤切口期间静脉压变化率 (ROCBP) 之间的相关性.
主要方法:
- 经过腹腔切除术的30名患者接受了0.7MAC的赛沃弗兰和持续的雷米芬坦尼尔输液.
- MECK是在巨性刺激后测量出来的.
- 在皮肤切口期间的ROCBP在相同的麻醉条件下测量.
主要成果:
- 在皮肤切口时观察到MECK和ROCBP之间存在很高的相关性 (R = -0.735,P <0.01).
- 观察到的相关性与先前在普罗波麻醉中发现的相关性相似 (R = -0.723).
- 线性回归方程的斜率为-0.27,与醇研究中发现的斜率相似 (-0.28).
结论:
- MECK作为一个可靠的ROCBP的预测指数在0.7MAC的sevoflurane麻醉下.
- 这些发现扩大了MECK作为超出propofol麻醉之外的同情反应预测者的适用性.
- MECK为优化麻醉深度和阿片类药物管理提供了一种有价值的工具.
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