放射治疗对鼻癌患者中鼻功能的影响
Fergus Kai-Chuen Wong1, Edwin Chun-Yin Wong2, Alvin Po-Ngai Chu1
1Department of ENT, Pamela Youde Nethersole Eastern Hospital, Hong Kong.
Ear, nose, & throat journal
|November 23, 2023
概括
放射治疗对鼻癌患者有显著的影响.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 在瘤学瘤学.
- 生活质量研究 研究 生命质量研究
背景情况:
- 鼻癌 (NPC) 放射治疗通常会导致鼻并发症.
- 关于NPC患者中鼻腔生活质量 (QoL) 和放射治疗后的变化,研究有限.
研究的目的:
- 评估放射治疗后NPC患者的鼻鼻功能和结构变化.
- 为了比较NPC患者和健康对照者之间的QoL,嗅觉功能和鼻腔生理学.
主要方法:
- 一项涉及14名NPC患者和14名健康对照者的病例控制研究.
- 评估的嗅觉值 (butanol值测试 - BTT) 和识别 (宾夕法尼亚大学气味识别测试 - UPSIT).
- 评估了鼻子症状 (SNOT-22),鼻子截面面积,鼻子流量和阻力 (声学鼻计和鼻计).
主要成果:
- 与对照组相比,NPC患者的嗅觉功能明显降低 (BTT,UPSIT) 和鼻腔症状得分更高 (SNOT-22) (P < .05).
- 两组之间在鼻子横截面积,鼻流量或鼻阻力方面没有发现统计学上显著的差异.
结论:
- 接受放射治疗的NPC患者经历了鼻鼻功能受损,特别是嗅觉和症状负担.
- 放射治疗后,包括鼻气流和阻力在内的鼻鼻结构变化需要进一步调查.
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