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模块化细胞因子基编辑促进表观基因组和基因组修改

Julian Weischedel1, Laurence Higgins2, Sally Rogers2

  • 1Institute of Experimental Immunology, University of Zurich, Zurich 8057, Switzerland.

Nucleic acids research
|November 23, 2023
PubMed
概括

研究人员开发了一种新的模块化编辑器,灵感来自激活诱导除氨酶 (AID),以复制其完整的基因组和表观基因组编辑能力. 这种新的工具箱促进了对AID生物学的理解,并改进了针对性基因编辑技术.

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