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Updated: Jul 10, 2025

Evaluation of Exon Inclusion Induced by Splice Switching Antisense Oligonucleotides in SMA Patient Fibroblasts
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作为精神分裂症的辅助治疗,酸减少了Ndel1寡酶活性

João Victor Nani1, Juliana Mayumi Ushirohira2, Nicholas J Bradshaw3

  • 1Departamento de Farmacologia, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil. Instituto Nacional de Ciência e Tecnologia Translacional em Medicina, Ribeirão Preto, SP, Brazil.

Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)
|November 23, 2023
PubMed
概括

在动物模型和精神分裂症患者中,酸 (sNP) 降低了核分布元类1 (Ndel1) 酶活性. 这表明sNP可能有利于精神分裂症患者,Ndel1可能是一个生物标志物.

关键词:
这是一个很好的方法. Ndel1动物模型动物模型生物标志物生物标志物精神分裂症是一种精神分裂症.化的酸.

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