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ALOX5AP是急性髓性白血病的一个新预后指标

Xin-Yi Chen1,2, Xiang-Mei Wen1,2, Wei Zhao2,3

  • 1Laboratory Center, Affiliated People's Hospital of Jiangsu University, Zhenjiang, Jiangsu, China.

Discover oncology
|November 23, 2023
PubMed
概括

与低甲基化相关的ALOX5AP过度表达表明急性髓性白血病 (AML) 的预后较差. 这一发现表明ALOX5AP可能作为AML进展和患者结局的生物标志物.

关键词:
ALOX5APAP的使用情况急性骨髓性白血病 (AML) 是一种急性骨髓性白血病.通过DNA甲基化.基因表达 基因表达 基因表达预测 预测 预测 预测

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Common myeloid progenitors (CMPs) are oligopotent cells that can differentiate into granulocytes and macrophages. Granulocytes and macrophages are essential for protecting the body against bacterial, viral, or fungal infections. They migrate from the bone marrow into the circulating blood to reach specific tissue sites where they differentiate and help in immune surveillance. However, they survive only for a few days and must be continuously made available to the organism to maintain a robust...