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Updated: Jul 10, 2025

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膜I型细胞可以导致KRAS诱导的肺腺癌

Minxiao Yang1, Hua Shen2, Per Flodby2

  • 1Department of Translational Genomics, University of Southern California, Los Angeles, CA 90089, USA; Department of Surgery, University of Southern California, Los Angeles, CA 90089, USA; Department of Biochemistry and Molecular Medicine, University of Southern California, Los Angeles, CA 90089, USA; Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90089, USA; Hastings Center for Pulmonary Research, University of Southern California, Los Angeles, CA 90089, USA.

Cell reports
|November 23, 2023
PubMed
概括

肺腺癌 (LUAD) 可能起源于1型 (AT1) 膜上皮细胞,而不仅仅是2型 (AT2) 细胞. 这一发现表明了基于其起源细胞的LUAD新的治疗策略.

关键词:
CP: 癌症 癌症 癌症KRT8(+) 中间细胞状态.克拉斯 (G12D) 信号发送.膜上皮细胞是膜上皮细胞.原始细胞的起源细胞肺癌是一种肺癌.瘤发生的发生因子.空间转录基因序列的测序

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