[在轻链amyloidosis患者的巨型舌头导致食障碍]
Juan José Gómez-Piña1, Dulce Mariana Quiroz2, Amairani Sierra-Hernández1
1Instituto Mexicano del Seguro Social, Centro Médico Nacional La Raza, Hospital de Especialidades "Antonio Fraga Mouret", Servicio de Medicina Interna. Ciudad de México, México.
Revista medica del Instituto Mexicano del Seguro Social
|November 23, 2023
概括
巨,或扩大的舌头,可以是一个罕见的氨基粉症的迹象. 这一案例突出了对巨的系统诊断方法,强调局部和系统形式的amyloidosis之间的区别.
科学领域:
- 医学 医学 医学 医学 医学
- 病理学 病理学 病理学
- 诊断 诊断 诊断 诊断
背景情况:
- 巨是全身性amyloidosis的一个罕见表现,在不到9%的病例中见到.
- 评估巨需要考虑各种差异性诊断,包括内分泌,瘤和沉积原因.
研究的目的:
- 提出一个系统的诊断方法,为患有巨发的患者.
- 强调区分局部性粉样性粉症和全身性粉症的重要性.
主要方法:
- 一个60岁的老人患有渐进性巨的病例报告.
- 诊断评估包括舌头活检与组织病理学和刚果红色染色.
- 进行骨髓活检以评估系统性参与.
主要成果:
- 舌头活检揭示了同质的氨酸性粉样类物质.
- 刚果红色染色证实了粉样蛋白与特有的双断裂.
- 骨髓活检显示了30%的血细胞,证实了软组织粉症.
结论:
- 巨光症需要彻底的诊断工作来确定潜在的原因.
- 区分局部性粉样性粉症和全身性粉症对于适当的管理至关重要.
- 气道损害是巨症患者的潜在并发症.
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