一种微生物muramidase提高了生长性能,并减少了在Eimeria和Clostridium perfringens挑战下 brojlers的肠道中的炎症细胞透
Cristiano Bortoluzzi1, Leticia C Bittencourt2, Estefania Perez-Calvo1
1DSM-Firmenich, Kaiseraugst, Switzerland.
Poultry science
|November 23, 2023
概括
在 brojlers中补充muramidase (MUR) 减少了炎症,并在Eimeria和Clostridium perfringens挑战下改善了生长性能. 这项研究突出了MUR的重点.
科学领域:
- 禽畜科学 禽畜科学 禽畜科学
- 动物营养 动物营养
- 免疫学 免疫学 免疫学
背景情况:
- 肉面临着由菌病和死性肠炎引起的重大健康挑战,影响其表现.
- 穆拉米达酶 (MUR) 是一种具有潜在抗微生物和抗炎性能的酶.
- 了解MUR对肠道病原体的疗效对于肉健康管理至关重要.
研究的目的:
- 为了评估Muramidase (MUR) 补充剂对受Eimeria和/或Clostridium perfringens挑战的肉的影响.
- 评估MUR对免疫反应,肠道健康和 brojlers的整体表现的影响.
主要方法:
- 在受控的挑战条件下,Cobb 500肉小进行了两个实验.
- 实验1涉及菌病和Clostridium perfringens挑战,评估免疫细胞透和基因表达.
- 实验2专注于Clostridium perfringens的挑战,评估生长性能,肉的产量和肠道吸收.
主要成果:
- 在受挑战的鸟类中,MUR补充剂降低了炎症标志物 (巨细胞,CD8+淋巴细胞) 和调节的细胞因子表达 (下调IL-8,上调IL-10).
- 在实验2中,MUR线性改善了生长性能,增加了乳房肉的产量,并提高了吸收能力.
- MUR表现出抗炎作用,有助于改善面临肠道挑战的 brojlers 的生长.
结论:
- 穆拉米达酶 (MUR) 补充剂有效地减轻了Eimeria和Clostridium perfringens在 brojlers中的负面影响.
- 补充MUR支持通过抗炎机制改善肠道健康和生长性能.
- MUR代表了一种有前途的营养策略,可以提高肉的弹性和生产力.
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