肺高血压中心肌应变参数是由体积功能的变化而不是血液动力学变化决定的
Volha Nizhnikava1, Ursula Reiter2, Gabor Kovacs3
1Department of Radiology, Medical University of Graz, Austria; Department of Radiology, Kantonsspital Graubuenden, Chur, Switzerland.
European journal of radiology
|November 23, 2023
概括
肺高血压 (PH) 与心肌压力降低有关. 左心室和右心室 (LV和VR) 应变变更密切地与体积功能有关,而不是PH中的肺动脉压力.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 生物医学工程 生物医学工程
背景情况:
- 肺高血压 (PH) 显著影响心脏功能.
- 评估心肌压力为心脏健康提供了洞察力.
- 心脏磁共振 (CMR) 特征跟踪是一种关键的成像技术.
研究的目的:
- 调查CMR衍生的心肌菌株与PH体积/血液动力学参数之间的关联.
- 确定PH患者心肌张力变化的关键决定因素.
- 为了评估心肌压在PH的诊断实用性.
主要方法:
- 67名PH患者和24名对照患者接受了右心导管 (RHC) 和3T CMR.
- 使用特征追踪量化LV和RV全球峰值菌株和菌株率.
- 统计分析包括t测试,相关性和回归分析.
主要成果:
- 与对照组相比,PH患者表现出减少的RV全球纵向应变 (RV-GLS) 和受损的RV缩应变率.
- RV-GLS是平均肺动脉压 (mPAP) 的最强单变相关体.
- 心肌应变参数与喷射分数比mPAP更强烈相关.
结论:
- 在PH中心肌应变损伤与改变的LV和RV体积功能比增加的mPAP更显著地相关.
- 在PH中,心肌菌株参数的诊断信息有限.
- 体积函数是PH中心肌张力变化的主要决定因素.
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